Comparative study of various cell lines susceptibility to cytopathic and non-cytopathic strains of Bovine viral diarrhea virus 1 and 2
نویسندگان
چکیده
منابع مشابه
Characterization of the immune response of cattle against non-cytopathic and cytopathic biotypes of bovine viral diarrhoea virus.
Cross-infection studies of normal calves infected with homologous pairs of non-cytopathic and cytopathic bovine viral diarrhoea virus (BVDV) showed significant differences in both humoral and cell-mediated immune responses against either biotype over a period of 5 months. Serological assays after primary intranasal inoculation showed striking significant (P < 0.05) differences between biotypes....
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Bovine Viral Diarrhea Virus (BVDV) is a single-stranded RNA virus in the Pestivirus genus within the Flaviviridae family. BVDV infections are seen in all ages and breeds of cattle worldwide and have significant economic impact due to productive and reproductive losses (Houe 2003). Two antigenically distinct genotypes of BVDV exist, type 1 and 2 (Ridpath et al. 1994). BVDV of both genotypes may ...
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In cytopathic bovine viral diarrhea virus genotype 1 (BVDV1) isolates, insertions are reported at position A (amino acid [aa] 1535) and position B (aa 1589). Insertions at position B predominate. In this survey it was found that in BVDV2, insertions at position A predominate. Possible reasons for this difference in relative frequency are discussed.
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A panel of monoclonal antibodies that recognize the two major glycoproteins of bovine viral diarrhea virus (BDV) was used to evaluate the antigenic relationship between cytopathic (CP) and noncytopathic (NCP) viruses isolated from cattle dead or dying from fatal BDV infections. Various unrelated BDV isolates were initially screened by indirect immunofluorescence with monoclonal antibodies direc...
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Bovine viral diarrhea virus (BVDV), a Flaviviridae pestivirus, is arguably one of the most widespread cattle pathogens worldwide. Each of its two genotypes has two biotypes, non-cytopathic (ncp) and cytopathic (cp). Only the ncp biotype of BVDV may establish persistent infection in the fetus when infecting a dam early in gestation, a time point which predates maturity of the adaptive immune sys...
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ژورنال
عنوان ژورنال: Acta Virologica
سال: 2009
ISSN: 1336-2305
DOI: 10.4149/av_2009_04_287